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Ansamitocin P-0
DM1
CAS Number: 139504-50-0
Product Info: Molecular Formula : C35H48ClN3O10S, Mol Wt : 738.3
IUPAC: [(1S,2R,5S,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate
Use/Class: Tubulin depolymerization
Stock Status: Ready Stock
DM4
CAS Number: 796073-69-3
Product Info: Molecular Formula : C38H54ClN3O10S, Mol Wt : 780.4
IUPAC: [(1S,2R,3R,5R,6S,16Z,18Z,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl-(4-methyl-4-sulfanylpentanoyl)amino]propanoate
Use/Class: Tubulin depolymerization
Stock Status: Ready Stock
Exatecan
CAS Number: 171335-80-1
Product Info: Molecular Formula : C24H22FN3O4, Mol Wt : 435.4
IUPAC: (10S,23S)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione
Use/Class: DNA topoisomerase I inhibitor
Stock Status: Ready Stock
MMAF
CAS Number: 745017-94-1
Product Info: Molecular Formula : C39H65N5O8, Mol Wt : 732
IUPAC: 2-[[3-methoxy-3-[(2R)-1-[3-methoxy-5-methyl-4-[methyl-[3-methyl-2-[[3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid
Use/Class: Tubulin polymerase inhibitor
Stock Status: Ready Stock
Auristatin F
Sibiromycin
CAS Number: 12684-33-2
Product Info: Molecular Formula : C24H33N3O7, Mol Wt : 475.5
IUPAC: (6R,6aS)-2-[(2S,3R,4R,5S,6S)-3,4-dihydroxy-4,6-dimethyl-5-(methylamino)oxan-2-yl]oxy-4,6-dihydroxy-3-methyl-8-[(E)-prop-1-enyl]-5,6,6a,7-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-11-one
Use/Class: A naturally produced glycosylated pyrrolobenzodiazepines
Stock Status: Ready Stock
DXD
CAS Number: 1599440-33-1
Product Info: Molecular Formula : C26H24FN3O6, Mol Wt : 493.5
IUPAC: N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]-2-hydroxyacetamide
Use/Class: DNA topoisomerase I Inhibitor
Stock Status: Ready Stock
N-Acetyl-Calicheamicin
CAS Number: 108212-76-6
Product Info: Molecular Formula : C57H76IN3O22S4, Mol Wt : 1410.4
IUPAC: S-[(2R,3S,4S,6S)-6-[[(2R,3S,4S,5R,6R)-5-[(2S,4S,5S)-5-[acetyl(ethyl)amino]-4-methoxyoxan-2-yl]oxy-4-hydroxy-6-[[(2S,5Z,9R,13E)-9-hydroxy-12-(methoxycarbonylamino)-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-2-bicyclo[7.3.1]trideca-1(12),5-dien-3,7-diynyl]oxy]-2-methyloxan-3-yl]amino]oxy-4-hydroxy-2-methyloxan-3-yl] 4-[(2S,3R,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5-iodo-2,3-dimethoxy-6-methylbenzenecarbothioate
Use/Class: DNA synthesis inhibitor
Stock Status: Ready Stock