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N-Acetyl-Calicheamicin
CAS Number: 108212-76-6
Product Info: Molecular Formula : C57H76IN3O22S4, Mol Wt : 1410.4
IUPAC: S-[(2R,3S,4S,6S)-6-[[(2R,3S,4S,5R,6R)-5-[(2S,4S,5S)-5-[acetyl(ethyl)amino]-4-methoxyoxan-2-yl]oxy-4-hydroxy-6-[[(2S,5Z,9R,13E)-9-hydroxy-12-(methoxycarbonylamino)-13-[2-(methyltrisulfanyl)ethylidene]-11-oxo-2-bicyclo[7.3.1]trideca-1(12),5-dien-3,7-diynyl]oxy]-2-methyloxan-3-yl]amino]oxy-4-hydroxy-2-methyloxan-3-yl] 4-[(2S,3R,4R,5S,6S)-3,5-dihydroxy-4-methoxy-6-methyloxan-2-yl]oxy-5-iodo-2,3-dimethoxy-6-methylbenzenecarbothioate
Use/Class: DNA synthesis inhibitor
Stock Status: Ready Stock
Dov-Val-Dil-OH?TFA
CAS Number: 133120-89-5
Product Info: Molecular Formula : C22H43N3O5, Mol Wt : 429.6
IUPAC: (3R,4S,5S)-4-[[(2S)-2-[[(2S)-2-(dimethylamino)-3-methylbutanoyl]amino]-3-methylbutanoyl]-methylamino]-3-methoxy-5-methylheptanoic acid
Use/Class: Intermediate for Quinstatin
Stock Status: Ready Stock
DM1-SMCC
CAS Number: 1228105-51-8
Product Info: Molecular Formula : C51H66ClN5O16S, Mol Wt : 1072.6
IUPAC: (2,5-dioxopyrrolidin-1-yl) 4-[[3-[3-[[(2S)-1-[[(1R,3R,5R,16E,18E,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl]oxy]-1-oxopropan-2-yl]-methylamino]-3-oxopropyl]sulfanyl-2,5-dioxopyrrolidin-1-yl]methyl]cyclohexane-1-carboxylate
Use/Class: Payload linker conjugate
Stock Status: Ready Stock
Doxorubicin
MMAE
CAS Number: 474645-27-7
Product Info: Molecular Formula : C39H67N5O7, Mol Wt : 718
IUPAC: (2S)-N-[(2S)-1-[[(3R,4R,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide
Use/Class: Microtubule inhibitor
Stock Status: Ready Stock
PDM-3
CAS Number: 72902-38-6
Product Info: Molecular Formula : C31H41ClN2O9, Mol Wt : 621.1
IUPAC: [(18E)-11-chloro-12,21-dihydroxy-20-methoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] 2-methylpropanoate
Use/Class: Produced by incubation of the corresponding methylated compound with Bacillus megaterium.
Stock Status: Ready Stock
Duocarmycin A
CAS Number: 118292-34-5
Product Info: Molecular Formula : C26H25N3O8, Mol Wt : 507.5
IUPAC: methyl (1R,4R,12S)-4-methyl-3,7-dioxo-10-(5,6,7-trimethoxy-1H-indole-2-carbonyl)-5,10-diazatetracyclo[7.4.0.01,12.02,6]trideca-2(6),8-diene-4-carboxylate
Use/Class: An antitumor antibiotic
Stock Status: Ready Stock
Val-Cit-PAB-MMAE
CAS Number: 644981-35-1
Product Info: Molecular Formula : C58H94N10O12, Mol Wt : 1123.4
IUPAC: [4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-(carbamoylamino)pentanoyl]amino]phenyl]methyl N-[1-[[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(2R)-3-[[(1R,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]-N-methylcarbamate
Use/Class: Tubulin polymerase inhibitor
Stock Status: Ready Stock
Spliceostatin A
CAS Number: 391611-36-2
Product Info: Molecular Formula : C28H43NO8, Mol Wt : 521.6
IUPAC: [(E,2S)-5-[[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dienyl]-2,5-dimethyloxan-3-yl]amino]-5-oxopent-3-en-2-yl] acetate
Use/Class: RNA synthesis inhibitor
Stock Status: Ready Stock
N-Me-L-Ala-maytansinol
CAS Number: 77668-69-0
Product Info: Molecular Formula : C32H44ClN3O9, Mol Wt : 650.2
IUPAC: [(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-(methylamino)propanoate
Use/Class: Tubulin polymerase inhibitor
Stock Status: Ready Stock